Gene description for CD81 |
Gene name |
CD81 molecule |
Gene symbol |
CD81 |
Other names/aliases |
CVID6 S5.7 TAPA1 TSPAN28 |
Species |
Homo sapiens |
Experiment description of studies that identified CD81 in Breast cancer cells |
1
|
Experiment ID | 333 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Slot blot
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Isolation/purification methods | Differential centrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR Microarray |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 334 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Slot blot
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 335 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Slot blot
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | BT-20 |
Isolation/purification methods | Differential centrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 336 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Slot blot
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF 10A |
Isolation/purification methods | Differential centrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 575 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | BT549 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 577 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 579 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ]
|
PubMed ID |
27894104
|
Organism | Homo sapiens |
Experiment description | Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. |
Authors | Hurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr. |
Journal name |
Oncotarget
|
Publication year | 2016 |
Sample | Breast cancer cells |
Sample name | MDA-MB-468 |
Isolation/purification methods | Differential centrifugation Polymer-based precipitation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1029 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
26378940
|
Organism | Homo sapiens |
Experiment description | Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. |
Authors | Clark DJ, Fondrie WE, Liao Z, Hanson PI, Fulton A, Mao L, Yang AJ. |
Journal name |
Anal Chem.
|
Publication year | 2015 |
Sample | Breast cancer cells |
Sample name | SKBR3B - 100 K pellet |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV150004: EV-METRIC:67%, 38%
|
|
|
9
|
Experiment ID | 1758 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35918900
|
Organism | Homo sapiens |
Experiment description | Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) |
Authors | Bauzá-Martinez J, Armony G, Pronker MF, Wu W. |
Journal name |
J Extracell Vesicles
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectometry Western blotting |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 1807 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36517516
|
Organism | Homo sapiens |
Experiment description | Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes |
Authors | Zhao D, Wu K, Sharma S, Xing F, Wu SY, Tyagi A, Deshpande R, Singh R, Wabitsch M, Mo YY, Watabe K. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | HCC1806 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting qPCR |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1937 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36193887
|
Organism | Homo sapiens |
Experiment description | Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity |
Authors | Ramos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H. |
Journal name |
Elife
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 1938 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
36193887
|
Organism | Homo sapiens |
Experiment description | Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity |
Authors | Ramos EK, Tsai CF, Jia Y, Cao Y, Manu M, Taftaf R, Hoffmann AD, El-Shennawy L, Gritsenko MA, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Liu X, Patel P, Wray B, Zhang Y, Zhang S, Moore RJ, Mathews JV, Schipma MJ, Liu T, Tokars VL, Cristofanilli M, Shi T, Shen Y, Dashzeveg NK, Liu H. |
Journal name |
Elife
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 1963 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 1964 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MCF10A |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
15
|
Experiment ID | 1965 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
16
|
Experiment ID | 1968 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density | 1.149 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
17
|
Experiment ID | 1969 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 6 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density | 1.174 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
18
|
Experiment ID | 1970 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density | 1.2 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
19
|
Experiment ID | 1971 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 8 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density | 1.227 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
20
|
Experiment ID | 2863 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
21
|
Experiment ID | 2864 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
22
|
Experiment ID | 2886 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231-luci (+) |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
23
|
Experiment ID | 3287 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
24
|
Experiment ID | 3288 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
25
|
Experiment ID | 3290 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 5 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
26
|
Experiment ID | 3291 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 6 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
27
|
Experiment ID | 3292 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 7 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
28
|
Experiment ID | 3293 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 8 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
29
|
Experiment ID | 3299 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Fraction 6 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
30
|
Experiment ID | 3303 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
31
|
Experiment ID | 3304 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
32
|
Experiment ID | 3305 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
33
|
Experiment ID | 3306 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
32848136
|
Organism | Homo sapiens |
Experiment description | ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
Authors | Fuentes P, Sesé M, Guijarro PJ, Emperador M, Sánchez-Redondo S, Peinado H, Hümmer S, Ramón Y Cajal S. |
Journal name |
Nat Commun
|
Publication year | 2020 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
34
|
Experiment ID | 1678 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 7-10 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
35
|
Experiment ID | 1678 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 7-10 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
36
|
Experiment ID | 1679 |
Identified molecule | Protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 - Exo-rich fractions 1-6 pooled |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
37
|
Experiment ID | 1963 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
35915084
|
Organism | Homo sapiens |
Experiment description | Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling |
Authors | Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA |
EV-TRACK |
-
|
|
|
38
|
Experiment ID | 2867 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
39
|
Experiment ID | 2870 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Mass spectrometry
|
PubMed ID |
30918259
|
Organism | Homo sapiens |
Experiment description | Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A |
Authors | Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC. |
Journal name |
Nat Commun
|
Publication year | 2019 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
40
|
Experiment ID | 1664 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Flow cytometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein mRNA |
Methods used in the study | RT-qPCR Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
41
|
Experiment ID | 1666 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Flow cytometry
|
PubMed ID |
34108659
|
Organism | Homo sapiens |
Experiment description | Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker |
Authors | Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. |
Journal name |
Nat Cell Biol
|
Publication year | 2021 |
Sample | Breast cancer cells |
Sample name | MDA-MB-231 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein mRNA |
Methods used in the study | RT-qPCR Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|